Change in overnight fasting blood parameters after a 50% high-fat diet at energy balance and fixed activity level
| Variable | BL1 | BL2 | HFD day 1 | HFD day 2 | HFD day 3 |
|---|---|---|---|---|---|
| Glucose (mg/dl) | 88.60 ± 7.38 | 89.77 ± 8.74 | 89.00 ± 9.76 | 89.40 ± 7.29 | 90.40 ± 9.03 |
| Insulin (mIU/ml) | 6.81 ± 3.02 | 6.98 ± 2.86 | 6.65 ± 3.00 | 6.07 ± 2.98* | 6.89 ± 2.67 |
| Free fatty acids (mmol) | 0.26 ± 0.08 | 0.28 ± 0.10 | 0.22 ± 0.08 | 0.25 ± 0.08 | 0.27 ± 0.10 |
Data are means ± SE. The HFD contained 50% fat. Repeated-measures ANOVA was used to test for time effects; P = 0.847, 0.130, and 0.047 for glucose, insulin, and free fatty acids, respectively.
* Post hoc comparisons of each HFD day versus average of the two baseline (BL) values were significant (P < 0.05; Dunnett’s adjustment).