TABLE 2

Comparison of normal control subjects with diabetic cohort

Control subjectsDiabetic cohortCrude comparisonAge-adjusted comparison
n*87178
Age (years)24.1 ± 8.616.6 ± 5.9<0.0001
GBM width (nm)342 ± 52425 ± 76<0.0001<0.0001
Vv (Mes/glom)0.200 ± 0.0320.218 ± 0.0440.0001<0.0001
Vv (MM/glom)0.085 ± 0.0160.098 ± 0.029<0.0001<0.0001
Vv (MC/glom)0.087 ± 0.0220.090 ± 0.0240.35630.2163
Sv (PGBM/glom)0.131 ± 0.0210.142 ± 0.0230.00010.2453
GV (1 × 106 mm3)1.67 ± 0.821.54 ± 0.540.40090.1861
TFS (1 × 103 mm2)0.226 ± 0.1230.218 ± 0.0720.73170.6362
Vv (Int/cortex)0.132 ± 0.0380.092 ± 0.026<0.00010.0008
  • Data are means ± SD. Significant values are in bold. P values result from t test between the normal control subjects and the diabetic cohort.

  • *

    * n = 87 for control subjects and 178 for diabetic cohort subjects, except for GV and TFS (control subjects, n = 30; diabetic cohort subjects, n = 145) and Vv (Int/cortex) (control subjects, n = 26; diabetic cohort subjects, n = 151).