TABLE 4

Renal hemodynamic function of type 2 diabetic patients with and without microalbuminuria after rosiglitazone or an alternative treatment

Without microalbuminuria
With microalbuminuria
NateglinideRosiglitazonePlacebo + previous oral antidiabetic drugRosiglitazone + previous oral antidiabetic drug
GFR (ml/min)118.7 ± 7.2103.2 ± 4.9*133.4 ± 9.8119.6 ± 8.7*
RPF (ml/min)550.3 ± 39.6554.9 ± 32.0568.4 ± 30.9567.5 ± 37.2
Filtration fraction (%)22.0 ± 1.418.9 ± 1.1*23.2 ± 1.720.5 ± 1.6*
Renal vascular resistance (mmHg · min−1 · l−1)110.3 ± 8.4105.9 ± 7.3108.8 ± 7.6106.1 ± 9.1
  • Data are means ± SE.

  • *

    * P < 0.05 vs. nateglinide or placebo.