TABLE 1

Association studies of the IVS3 + 68C>T variant of PYY with overweight, obesity, and type 2 diabetes in Danish whites

GroupnCCCTTTT allele frequency (95% CI)*Pallelefrequency*Pgenotypedistribution
Subjects with BMI <25 kg/m22,6762,220 (83.0)432 (16.1)24 (0.9)9.0 (8.2–9.7)
Subjects with 25 ≤ BMI < 30 kg/m22,3661,968 (83.2)372 (15.7)26 (1.1)9.0 (8.1–9.8)0.990.72
Subjects with BMI ≥30 kg/m21,048865 (82.5)172 (16.4)11 (1.0)9.3 (8.0–10.5)0.700.89
Glucose-tolerant subjects4,6753,911 (83.7)716 (15.3)48 (1.0)8.7 (8.1–9.3)
Type 2 diabetic patients1,3811,167 (84.5)206 (14.9)8 (0.6)8.0 (7.0–9.1)0.290.25
  • Data are n (%), unless otherwise indicated. Top three rows:

  • *

    * P values are calculated with χ2 test and describe the significance levels comparing the lean and overweight group and the lean and obese group. Bottom two rows: *P values are calculated with χ2 test and describe the significance levels comparing the glucose-tolerant subjects and the type 2 diabetic patients.