TABLE 1

Trends in increased body weight gain and progressive hyperinsulinemia in ZF rat pups

20 day
22 day
24 day
26 day
28 day
Body Weight (g)Blood Insulin (ng/ml)Body Weight (g)Blood Insulin (ng/ml)Body Weight (g)Blood Insulin (ng/ml)Body Weight (g)Blood Insulin (ng/ml)Body Weight (g)Blood Insulin (ng/ml)
ZLC34.4 ± 1.10.25 ± 0.0540.8 ± 1.060.34 ± 0.0449.0 ± 1.40.42 ± 0.0557.9 ± 1.60.56 ± 0.2964.6 ± 1.10.38 ± 0.03
ZF37.4 ± 1.70.26 ± 0.0544.3 ± 2.10.32 ± 0.0354.8 ± 2.7*0.75 ± 0.1167.4 ± 3.20.62 ± 0.1875.9 ± 2.43.24 ± 1.53*
  • Values represent measurements from the 28-day group comprised of 6 ZF and 11 ZLC rats*. Body weight and blood insulin were measured from fed rats at the same time each morning.

  • *

    * P < 0.05;

  • P < 0.01;

  • P < 0.001.