TABLE 1

Subject characteristics

NondiabeticObeseType 2 diabetic
n887
Age (years)47.25 ± 4.843.5 ± 4.048.0 ± 5.2
Weight (kg)75.2 ± 5.496.7 ± 4.0110.0 ± 5.4
BMI (kg/m2)24.4 ± 1.233.3 ± 1.06*37.1 ± 2.64*
Fasting plasma glucose (mmol/l)5.09 ± 0.125.1 ± 0.111.3 ± 1.5*
Glucose infusion rate (mg · kg−1 · min−1)9.9 ± 0.937.0 ± 0.372.26 ± 0.76*
Basal insulin (pmol/l)66.7 ± 10125.36 ± 26315 ± 78
Insulin after 300-min clamping (pmol/l)1,070 ± 471,290 ± 961,090 ± 74
Basal plasma free fatty acids (μmol/l)346 ± 36400 ± 30§750 ± 120
Free fatty acids after insulin clamping (μmol/l)19 ± 3.816 ± 3.5270 ± 100
Triacylglycerol (mg/dl)88.75 ± 6.8128.6 ± 21390 ± 127
  • Data are means ± SE. All P values were determined by comparing with nondiabetic subjects.

  • *

    * P < 0.005;

  • P < 0.05;

  • P < 0.02;

  • §

    § NS;

  • P = 0.05.