TABLE 4

Association of RANTES with type 2 diabetes and IGT (multiple logistic regression models)

RANTES (ng/ml)Quartile 1 (≤14.22)Quartile 2 (>14.22/≤19.93)Quartile 3 (>19.93/≤29.28)Quartile 4 (>29.28)P for trend
Type 2 diabetes vs. control subjects
Model 11.01.11 (0.62–1.99)1.47 (0.84–2.58)3.26 (1.93–5.51)*<0.0001
Model 21.00.98 (0.53–1.84)1.13 (0.62–2.08)2.42 (1.38–4.23)0.0006
Model 31.01.05 (0.54–2.03)1.12 (0.59–2.13)2.09 (1.15–3.81)0.0093
Model 41.01.07 (0.54–2.11)1.07 (0.55–2.09)1.96 (1.05–3.66)0.024
IGT vs. control subjects
Model 11.01.18 (0.65–2.13)2.37 (1.38–4.09)2.99 (1.75–5.11)*<0.0001
Model 21.01.13 (0.61–2.08)2.32 (1.31–4.08)2.76 (1.58–4.80)*<0.0001
Model 31.01.17 (0.62–2.21)2.30 (1.28–4.13)2.71 (1.52–4.83)*0.0001
Model 41.01.09 (0.57–2.09)2.07 (1.14–3.78)2.47 (1.37–4.45)0.0004
  • Data are ORs (95% CI) for association of type 2 diabetes or IGT with RANTES. Quartiles are based on data from normoglycemic control subjects.

  • *

    * P < 0.001,

  • P < 0.01,

  • P < 0.05 compared with quartile 1. Model 1: crude; model 2: adjusted for BMI; model 3: adjusted for BMI, sex, age, hypertension, LDL cholesterol, HDL cholesterol, and uric acid; model 4: model 3 with additional adjustment for log-CRP and log–IL-6.