TABLE 5

Association of IP-10 with type 2 diabetes and IGT (multiple logistic regression models)

IP-10 (pg/ml)Quartile 1 (≤193.8)Quartile 2 (>193.8/≤281.0)Quartile 3 (>281.0/≤438.4)Quartile 4 (>438.4)P for trend
Type 2 diabetes vs. control subjects
Model 11.00.89 (0.53–1.50)1.19 (0.72–1.96)0.91 (0.54–1.52)NS
Model 21.00.91 (0.52–1.60)1.06 (0.61–1.82)0.74 (0.42–1.30)NS
Model 31.00.89 (0.49–1.62)0.98 (0.55–1.74)0.58 (0.32–1.07)NS
Model 41.00.88 (0.47–1.64)0.97 (0.53–1.77)0.48 (0.26–0.92)*NS
IGT vs. control subjects
Model 11.01.03 (0.61–1.76)1.62 (0.98–2.67)1.31 (0.78–2.19)NS
Model 21.01.13 (0.65–1.97)1.86 (1.10–3.15)*1.33 (0.77–2.28)NS
Model 31.01.07 (0.60–1.93)1.73 (0.99–3.03)1.18 (0.66–2.10)NS
Model 41.01.02 (0.56–1.87)1.69 (0.95–3.00)0.97 (0.53–1.77)NS
  • Data are ORs (95% CI) for association of type 2 diabetes or IGT with IP-10. Quartiles are based on data from normoglycemic control subjects.

  • *

    * P < 0.05 compared with quartile 1. Model 1: crude; model 2: adjusted for BMI; model 3: adjusted for BMI, sex, age, hypertension, LDL cholesterol, HDL cholesterol, and uric acid; model 4: model 3 with additional adjustment for log-CRP and log–IL-6.