TABLE 2

Effect of IL-6, insulin, and/or AICAR treatment on AMPK and ACC phosphorylation in L6 myotubes

VehicleIL-6InsulinIL-6 + insulinAICAR
pAMPK/AMPK1.00 ± 0.201.83 ± 0.13*1.29 ± 0.601.78 ± 0.12*1.95 ± 0.20*
pACC/ACC1.00 ± 0.161.29 ± 0.08*1.01 ± 0.261.14 ± 0.18*1.72 ± 0.38
  • Data are means ± SE (n = 6).

  • *

    * Difference from Vehicle. AICAR, 5-amino-4-imidazolecarboxamide riboside.