TABLE 1

Mean daily 5-h postdose blood glucose levels in mice treated with control or glucagon mAbs for 5 days

Mean postdose blood glucose (mmol/l)
Control mAb treatmentGlucagon mAb treatment
Basal (control mAbs)13.0 ± 0.413.3 ± 0.6
Treatment (control/glucagon mAbs)12.3 ± 0.49.1 ± 0.3*
  • Data are means ± SE, n = 10 mice/group.

  • *

    * P < 0.01 vs. control mAbs 1st week in a paired t test;

  • P < 0.001 vs. control mAbs 2nd week in unpaired t test.