TABLE 3

Quantitative trait studies of the rs4784675, rs7178130, rs6108572, and variant rs221667 in 622 French-Caucasian obese children

z score of BMIRebound mean agez score of heightFasting insulinInsulin at t = 120Fasting glucoseGlucose at t = 120Apolipo-protein BFasting triglycerideHDL-to-total cholesterol ratio
BBS2 rs47846750.910.050.870.450.560.680.390.020.90.5
    GG/GC4.08 ± 1.22.38 ± 1.51.93 ± 1.413.85 ± 10.246.6 ± 40.14.91 ± 0.45.55 ± 0.90.81 ± 0.21.02 ± 0.50.29 ± 0.1
    CC4.12 ± 1.11.28 ± 1.51.87 ± 0.912.6 ± 6.741.2 ± 41.14.85 ± 0.55.27 ± 0.90.92 ± 0.21.01 ± 0.70.27 ± 0.1
BBS4 rs71781300.960.550.230.930.420.150.770.970.230.89
    GG/GA4.07 ± 1.22.34 ± 1.51.96 ± 1.413.74 ± 10.948.1 ± 40.14.9 ± 0.45.54 ± 0.90.82 ± 0.21.04 ± 0.50.29 ± 0.1
    AA4.08 ± 1.62.53 ± 1.51.71 ± 1.413.6 ± 8.745.8 ± 39.15.01 ± 0.45.6 ± 1.00.82 ± 0.20.94 ± 0.40.29 ± 0.01
BBS6 rs61085720.10.730.210.080.720.10.90.030.020.16
    AA/AT4.12 ± 1.22.35 ± 1.51.96 ± 1.414.07 ± 11.646.8 ± 40.64.93 ± 0.45.55 ± 0.90.81 ± 0.21.01 ± 0.50.29 ± 0.4
    TT3.88 ± 1.22.41 ± 1.71.8 ± 1.212.5 ± 7.446.1 ± 39.74.82 ± 0.55.51 ± 0.90.85 ± 0.21.07 ± 0.50.28 ± 0.7
BBS6 rs2216670.270.0080.0050.570.210.080.0060.020.0040.05
    CC/CG4.1 ± 1.22.39 ± 1.51.96 ± 1.413.95 ± 10.545.8 ± 40.44.92 ± 0.45.5 ± 0.90.82 ± 0.21.01 ± 0.50.29 ± 0.1
    GG3.82 ± 1.11.57 ± 1.51.64 ± 1.312.23 ± 7.253.5 ± 34.54.77 ± 0.55.95 ± 0.70.89 ± 0.31.24 ± 0.60.27 ± 0.1
  • Data are means ± SE or P values. No P values survived simple Bonferroni correction for 40 tests (10 phenotypes × 4 SNPs).