TABLE 2

Single-marker family-based association analysis of SNP markers in the PTPN22 gene

SNP numbercDNA positiondbSNP numberGenomic position*AlleleMAFFBAT
zP
1rs1235005114129479C/G0.4442.8060.005015
2rs2488457114127410G/C0.2403.1570.001596
3rs1217414114124709C/T0.2740.0140.989227
4rs1217418114113273C/T0.4632.4820.013070
51858rs2476601114089610C/T0.1264.1550.000033
6rs2797415114089135C/T0.2803.0870.002023
7rs3761935114084570A/C0.182−0.3010.763082
82250114084256G/C0.0062.2140.026857
9rs1217388114076518T/C0.2763.0090.002619
10rs2476599114075501C/T0.2720.0140.989156
113′ UTRrs3811021114068705T/C0.181−0.2990.765138
  • *

    * Positions are according to NCBI (National Center for Biotechnology Information) Build 35, and the SNPs are listed from the 5′ end of PTPN22 to the 3′ end;

  • common allele is listed first;

  • calculated for the minor allele. MAF, minor allele frequency; UTR, untranslated region.