TABLE 4

Parameters describing the kinetics for [18F]FDG uptake into soleus and tibialis anterior muscles during fasting and insulin-stimulated conditions

Fasting
Insulin stimulated
SoleusTibialis anteriorSoleusTibialis anterior
k1 (ml/ml per min)0.025 ± 0.002 (2 ± 0.2%)*0.017 ± 0.001 (2 ± 0.2%)0.019 ± 0.001 (4 ± 0.6%)*0.013 ± 0.003 (5 ± 2%)
k2 (min−1)0.170 ± 0.013 (4 ± 0.5%)0.158 ± 0.012 (6 ± 0.9%)0.081 ± 0.025 (45 ± 15%)0.063 ± 0.042 (66 ± 24%)
k3 (min−1)0.015 ± 0.001 (17 ± 3%)0.028 ± 0.004 (22 ± 4%)0.184 ± 0.027 (37 ± 12%)0.168 ± 0.058 (44 ± 21%)
k4 (min−1)0.013 ± 0.002 (84 ± 9%)0.026 ± 0.005 (54 ± 7%)0.011 ± 0.003 (109 ± 40%)0.026 ± 0.014 (127 ± 36%)
k5 (min−1)0.025 ± 0.005 (81 ± 10%)0.025 ± 0.003 (39 ± 7%)0.039 ± 0.009 (62 ± 15%)0.022 ± 0.006 (121 ± 56%)
K0.0013 ± 0.0004 (15 ± 4%)0.0014 ± 0.0004 (8 ± 3%)0.0124 ± 0.001 (2 ± 1%)0.083 ± 0.002 (5 ± 3%)
Vec (ml/ml)0.139 ± 0.005 (3 ± 0.4%)*0.103 ± 0.006 (4 ± 0.7%)0.090 ± 0.010 (30 ± 9%)0.117 ± 0.034 (53 ± 15%)
Vic (ml/ml)0.066 ± 0.014 (67 ± 7%)0.061 ± 0.009 (32 ± 6%)0.365 ± 0.058 (60 ± 15%)0.459 ± 0.154 (117 ± 55%)
  • Data are means ± SE. The values in parentheses are the errors for parameter estimation.

  • *

    * P < 0.05 vs. tibialis anterior;

  • P < 0.05 vs. basal.