TABLE 1

TCF7L2 rs7903146 T at-risk allele association with hyperglycemia during a 9-year follow-up of a general French population

AnalysisC/C (HG/control)C/T (HG/control)T/T (HG/control)Allelic OR (95% CI)P
A1252/2,176 = 0.116226/1,878 = 0.12064/380 = 0.1681.14 (1.00–1.31)0.049
A2200/1,472 = 0.136215/1,200 = 0.17945/253 = 0.1781.20 (1.04–1.40)0.014
A3452/1,472 = 0.307441/1,200 = 0.368109/253 = 0.4311.19 (1.07–1.33)0.002
  • The genotypic distributions were in agreement with Hardy-Weinberg equilibrium. A1: At baseline, all participants. A2: Control: participants followed 9 years and remaining normoglycemic over the 9 years. HG: incident cases of hyperglycemia over the 9 years. A3: Control: participants followed 9 years and remaining normoglycemic over the 9 years. HG: participants hyperglycemic at baseline and incident cases of hyperglycemia.