TABLE 4

CRE sites within mammalian insulin promoters

SpeciesCRE1CRE2CRE3CRE4
Consensustgacgtca
Humantgacccgctgacgacctgcatcagtgcgtcag
Chimpanzeetgacccgctgacgacctgcatcagtgcgtcag
Gorillatgacccgctgacgacctgcatcagtgcgtcag
OrangutantgacccgctgaTgacctgcatcagtgcgtcag
Rhesus macaquetgacGTgctgacgacctgcatcagcgcgtcag
African green monkeytgacccgctgacgacctgcatcagcgcgtcag
Owl monkeytgacgacctgcatcaC
PigtgaTgacc
Rat 1tgacgTcc
Rat 2tgTTgTcc
Mouse 1tgaTgTcc
Mouse 2tgacgTcc
Dogtgacgacc
CowtgacgGcc
  • The CRE site octamers present in the reviewed species are listed with deviations from the consensus CRE motif underlined and differences from the equivalent human CRE site shown in capital letters.