TABLE 1

Initial and final body weights and blood glucose concentrations in nondiabetic control mice and ob/ob mice with and without fidarestat treatment

Body weight (g)
Blood glucose (mmol/l)
InitialFinalInitialFinal
Control20.6 ± 0.4029.0 ± 0.957.9 ± 0.178.0 ± 0.20
Control + F20.4 ± 0.4928.0 ± 1.108.6 ± 0.288.1 ± 0.31
ob/ob46.9 ± 0.95*57.1 ± 1.36*18.8 ± 2.16*17.6 ± 1.77*
ob/ob + F46.6 ± 0.84*57.9 ± 1.03*19.0 ± 2.32*15.9 ± 2.83*
  • Data are means ± SE; n = 12–21 per group.

  • *

    * Significantly different from nondiabetic controls (P < 0.01). F, fidarestat.