TABLE 2

Multinomial logistic regression models for the relationship between the glucose tolerance categories and sex and HRT use

Isolated IFGIsolated IGTIFG + IGTDiabetes
Sex
    Model 1
        Sex0.45 (0.33–0.63)1.77 (1.34–2.34)0.99 (0.57–1.71)0.94 (0.75–1.17)
    Model 2
        Sex0.45 (0.33–0.63)1.78 (1.34–2.36)0.76 (0.58–1.00)0.95 (0.75–1.20)
        Ethnicity1.04 (0.90–1.20)1.06 (0.93–1.20)1.15 (1.01–1.32)1.30 (1.16–1.47)
        Age1.01 (1.00–1.02)1.04 (1.03–1.05)1.02 (1.01–1.03)1.05 (1.04–1.06)
    Model 3
        Sex0.43 (0.30–0.63)1.76 (1.30–2.38)0.78 (0.58–1.07)1.00 (0.77–1.30)
        Ethnicity1.01 (0.86–1.18)1.03 (0.91–1.18)1.10 (0.95–1.27)1.26 (1.11–1.44)
        Age1.01 (0.99–1.02)1.04 (1.03–1.05)1.03 (1.02–1.04)1.06 (1.05–1.07)
        Waist circumference1.02 (1.01–1.03)1.01 (1.00–1.02)1.04 (1.03–1.05)1.04 (1.03–1.05)
    Model 4
        Sex0.45 (0.30–0.67)1.81 (1.32–2.49)0.81 (0.58–1.15)1.27 (0.88–1.82)
        Ethnicity0.96 (0.82–1.13)1.03 (0.90–1.19)1.03 (0.89–1.20)1.03 (0.88–1.22)
        Age1.01 (0.99–1.02)1.03 (1.02–1.05)1.02 (1.01–1.03)1.06 (1.05–1.07)
        Waist circumference1.01 (0.99–1.02)1.01 (0.99–1.02)1.02 (1.00–1.03)1.01 (0.99–1.02)
        ln(fasting insulin)3.17 (2.02–4.98)2.34 (1.76–3.11)7.38 (5.07–10.73)24.43 (15.14–39.43)
        ln(ΔI0–30 /ΔG0–30)0.50 (0.36–0.69)0.43 (0.33–0.56)0.19 (0.13–0.26)0.05 (0.03–0.07)
HRT use
    Model 1
        HRT use0.70 (0.33–1.48)1.84 (1.14–2.98)0.99 (0.57–1.71)0.88 (0.58–1.35)
    Model 2
        HRT use0.76 (0.35–1.61)2.12 (1.28–3.52)1.09 (0.63–1.89)1.00 (0.66–1.53)
        Ethnicity0.94 (0.72–1.24)0.94 (0.74–1.20)0.98 (0.76–1.62)1.09 (0.88–1.33)
        Age1.02 (0.99–1.05)1.04 (1.01–1.07)1.03 (0.99–1.05)1.03 (1.01–1.05)
    Model 3
        HRT use0.84 (0.32–2.19)2.01 (1.16–3.48)1.24 (0.68–2.28)0.94 (0.59–1.52)
        Ethnicity0.89 (0.63–1.26)0.91 (0.70–1.18)0.94 (0.72–1.24)1.07 (0.86–1.34)
        Age1.02 (0.99–1.06)1.03 (1.00–1.06)1.03 (1.00–1.06)1.03 (1.01–1.06)
        Waist circumference1.03 (1.00–1.06)1.01 (0.99–1.03)1.03 (1.01–1.05)1.02 (1.00–1.04)
    Model 4
        HRT use0.95 (0.35–2.57)2.18 (1.19–3.96)1.31 (0.63–2.73)1.24 (0.66–2.32)
        Ethnicity0.83 (0.58–1.19)0.85 (0.64–1.11)0.79 (0.58–1.07)0.81 (0.61–1.08)
        Age1.04 (0.99–1.08)1.04 (1.01–1.08)1.06 (1.02–1.10)1.06 (1.03–1.10)
        Waist circumference1.02 (0.98–1.05)1.01 (0.98–1.03)1.01 (0.99–1.03)0.99 (0.97–1.02)
        ln(fasting insulin)3.53 (0.93–13.39)2.42 (1.36–4.32)13.68 (6.56–28.51)21.62 (9.59–48.75)
        ln(ΔI0–30 /ΔG0–30)0.59 (0.29–1.20)0.50 (0.29–0.86)0.16 (0.08–0.34)0.06 (0.03–0.15)
  • Data are RR(95% CI). All models were corrected for familial clustering. For all models, NGT is the comparison group. The reference group for sex is men. The reference group for HRT use is non-HRT users.