TABLE 1

Insulin clamp characteristics in C57BL/6J mice by sampling method

Cut tailArterial catheter
Glucose (mg/dl)123 ± 5129 ± 6
GIR (mg · kg−1 · min−1)56 ± 557 ± 7
Insulin (μU/ml)29 ± 337 ± 6
EndoRa (mg · kg−1 · min−1)5 ± 1−5 ± 3*
Rd (mg · kg−1 · min−1)62 ± 750 ± 4*
  • Data are means ± SE and represent the average of five measurements taken during the last 40 min of the clamp period. For cut tail–sampled mice, glucose and GIR values represent data obtained from n = 12 mice, and insulin, endoRa, and Rd values represent data obtained from a subset of mice (n = 4). All values for artery-sampled mice represent data obtained from n = 7 mice.

  • *

    * P < 0.05 vs. cut tail.