TABLE 2

Postpartum diabetes risk in islet autoantibody-negative women with GDM

Variable categoryn8-year diabetes riskSignificance (P)HR* (95% CI)Significance (P)
Insulin in pregnancy
    No17823.2 (15.4–31.0)
    Yes9284.5 (75.3–93.7)<0.00016.2 (4.1–9.6)<0.0001
BMI
    <30 kg/m218734.6 (26.2–42.0)
    >30 kg/m28050.1 (39.0–61.2)0.0032.2 (1.5–3.3)<0.0001
First-degree relatives with diabetes
    No15538.1 (28.7–47.5)
    Yes9857.3 (45–69.6)0.101.4 (0.9–2.1)0.10
Age at delivery
    <35 years20746.4 (37.9–54.9)
    >35 years6353.4 (37.1–69.6)0.451.2 (0.8–1.9)0.41
Pregnancy duration
    ≥37 weeks24948.5 (40.6–56.4)
    <37 weeks2137.% (12.0–62.0)0.540.8 (0.3–1.7)0.50
Birth weight of child
    1st tertile9045.4 (30.2–60–6)
    2nd tertile9040.6 (27.2–54.0)0.750.9 (0.5–1.6)0.75
    3rd tertile9050.5 (35.7–66.3)0.721.0 (0.6–1.7)0.94
Previous pregnancies
    None12533.0 (22.5–43.5)
    18853.9 (39.8–68.0)0.341.4 (0.9–2.3)0.16
    23664.8 (39.9–88.7)0.541.6 (0.9–3.0)0.12
    >22175.0 (53.4–96.6)0.00014.2 (2.2–8.3)0.0001
Serum CRP at 9 months
    1st quartile3632.9 (12.5–53.3)
    2nd–4th quartile11155.8 (44.4–67.2)0.042.4 (1.2–4.8)0.02
  • Data are % (95% CI), unless otherwise indicated.

  • *

    * Unadjusted HR calculated from Cox proportional hazards model.