TABLE 2

PPARG C1431T genotype frequencies, according to glycemic status after 6 years in subjects who were normoglycemic at baseline: the DESIR study

CCCTTT
Normoglycemic2,493 (77.6)673 (20.9)47 (1.5)
IFG125 (83.3)24 (16.0)1 (0.7)
Type 2 diabetes37 (86.0)6 (14.0)0 (0)
Hyperglycemia (IFG + type 2 diabetes)162 (84.0)30 (15.5)1 (0.5)
OR for hyperglycemia (95% CI)*10.68 (0.45–1.02)0.28 (0.04–2.09)
OR for hyperglycemia (95% CI)* (T+ vs. CC)10.65 (0.44–0.97)§
  • Data are n (%), unless otherwise indicated.

  • *

    * By multiple logistic regression analyses (adjustment for sex, age, BMI). Codominant model (number of T alleles: 0, 1, 2, considered as a continuous variable): OR for hyperglycemia (95% CI) = 0.65 (0.45–0.95), P = 0.027.

  • P = 0.062;

  • P = 0.428;

  • §

    § P = 0.036.