TABLE 5

APM1 G-11391A genotype frequencies, according to glycemic status after 6 years in subjects who were normoglycemic at baseline: the DESIR study

GGGAAA
Normoglycemic2,702 (82.2)554 (16.9)31 (0.9)
IFG116 (76.3)34 (22.4)2 (1.3)
Type 2 diabetes34 (77.3)10 (22.7)0 (0)
Hyperglycemia (IFG + type 2 diabetes)150 (76.5)44 (22.4)2 (1.0)
OR for hyperglycemia (95% CI)*11.62 (1.13–2.33)1.65 (0.38–7.13)
OR for hyperglycemia (95% CI)* (A+ vs. GG)11.62 (1.14–2.31)
  • Data are n (%), unless otherwise indicated.

  • *

    * By multiple logistic regression analyses (adjustment for sex, age, BMI). Codominant model (number of A alleles, 0, 1, 2, considered as a continuous variable): OR for hyperglycemia (95% CI) = 1.55 (1.12–2.14), P = 0.008.

  • P = 0.008;

  • P = 0.505;

  • §P = 0.007.