TABLE 3

Hypothalamic insulin receptor and OB-Rb mRNA

SexnInsulin receptor mRNAOB-Rb mRNA
Male10100.0 ± 4.0100.0 ± 6.9
Female10167.7 ± 8.5*72.98 ± 1.4*
OVX18193.4 ± 11.9*80.29 ± 3.9*
Castrated male10129.8 ± 6.4*91.75 ± 5.4
Intact male + 17 β-estradiol10131.0 ± 7.8*92.47 ± 8.6
  • Data are mean ± SE. Whole hypothalamus was extracted and assayed for insulin receptor and OB-RB mRNA.

  • *

    * ANOVA revealed significant differences (P < 0.05) from intact male rats;

  • represents significant differences from intact females.