TABLE 4

Haplotypic association analysis of PYGM SNPs (rs625172, rs565688, and rs2073798) with DI

HaplotypeFrequencyDispositionP values for each model
Haplo-genotype mean DI ± SD
DominantAdditiveRecessive+/+*+/−−/−
CTC0.54Neutral0.6790.5340.0891,501 ± 1,1181,377 ± 1,2471,432 ± 1,312
TAA0.290.0200.1350.4591,452 ± 1,1261,395 ± 1,3731,440 ± 1,137
TTA0.15Neutral0.5990.8280.2741,572 ± 8391,266 ± 1,3181,471 ± 1,211
  • *

    * DI ± SD for individuals whose haplo-genotype has two copies of the haplotype of interest;

  • DI ± SD for individuals whose haplo-genotype has one copy of the haplotype of interest and any other haplotype;

  • DI ± SD for individuals whose haplo-genotype has any other haplotype combination. Boldface indicates statistical significance.