TABLE 2

Gravimetric, metabolic, and hormone data for db/db mice

MeasurementControldb/db
n1212
Body weight (g)
    Initial18.8 ± 1.325.9 ± 5.5*
    1 month23.4 ± 1.645.7 ± 3.6
    3 months26.0 ± 1.846.1 ± 8.5
Blood glucose (mmol/l)
    Initial8.7 ± 1.214.0 ± 8.7
    1 month7.2 ± 1.425.1 ± 5.3
    3 months7.0 ± 0.931.7 ± 3.7
Cholesterol (mmol/l)
    3 months1.92 ± 0.212.56 ± 0.66
Hormone levels (pmol/l)
    Insulin127 ± 93374 ± 353
    Leptin63 ± 15382 ± 194
    Amylin6 ± 356 ± 29
  • Data are means ± SD. Hormone levels measured after 3 months of hyperglycemia with the LINCOplex kit according to manufacturer’s instructions. Significantly different from controls by Students t test:

  • *

    * P < 0.001;

  • P < 0.0001;

  • P < 0.01.