TABLE 1

Main clinical and laboratory characteristics of patients with microalbuminuria (case subjects) and normoalbuminuria (control subjects) included in the main study

VariableMicroalbuminuria (case subjects)Normoalbuminuria (control subjects)
Patients (n)5050
Sex (male/female)42/842/8
Age (years)59.1 ± 8.758.4 ± 8.6
Duration of diabetes (months)98.9 ± 84.295.5 ± 78.1
Smoking (no/yes/ex-smokers)24/18/824/21/5
BMI (kg/m2)28.7 ± 3.528.5 ± 3.6
sBP (mmHg)141 ± 18140 ± 18
dBP (mmHg)83 ± 983 ± 11
MAP (mmHg)103 ± 11102 ± 12
A1C (%)7.09 ± 2.13*6.05 ± 1.92
GDR (mg · kg−1 · min−1)5.20 ± 1.91*6.86 ± 2.88
Serum creatinine (μmol/l)77 ± 2077 ± 18
GFR (ml/min per 1.73 m2)107.9 ± 24.63115.80 ± 24.28
AER (μg/min)61.41 ± 40.52*7.58 ± 4.85
Total cholesterol (mmol/l)5.23 ± 0.835.05 ± 0.75
HDL cholesterol (mmol/l)1.11 ± 0.211.11 ± 0.31
LDL cholesterol (mmol/l)4.12 ± 0.833.91 ± 0.73
Triglycerides (mmol/l)1.64 ± 0.801.41 ± 0.62
Diet/sulfonylureas/metformin/insulin3/37/24/1014/34/16/6
ACEi/diuretics/α-blockers/CCB4/19/7/130/7/8/4
Statins/fibrates4/07/0
  • Data are frequency or means ± SD. ACEi, ACE inhibitor; CCB, calcium channel blocker; dBP, diastolic blood pressure; MAP, mean arterial pressure; sBP, systolic blood pressure.

  • *

    * P < 0.05 vs. patients with normoalbuminuria.

  • Fisher’s exact test: diet, P = 0.006; ACEi, P = 0.044; diuretics, P = 0.006; CCB, P = 0.01.