TABLE 1

Clinical and biochemical characteristics of the study subjects

Nondiabetic control subjectsPatients with type 2 diabetesP
n (male/female)481/650278/273
Age (years)47 ± 1461 ± 110.46
Age at diagnosis (years)52 ± 11
Duration of diabetes (years)11 ± 9
Treatment for diabetes (diet/oral agents/insulin)37/346/168
BMI (kg/m2)29.5 ± 6.530.1 ± 5.80.03
Systolic blood pressure (mmHg)122 ± 15137 ± 180.0001
Diastolic blood pressure (mmHg)78 ± 1081 ± 100.03
Fasting glucose (mg/dl)92 ± 10164 ± 710.0001
2-h postchallenge glucose (mg/dl) (n = 734)116 ± 32
HbA1c (%)5.3 ± 0.67.5 ± 2.40.0001
Total cholesterol (mg/dl)203 ± 41205 ± 440.47
HDL cholesterol (mg/dl)52 ± 1445 ± 150.0001
Triglycerides (mg/dl)125 ± 68163 ± 1000.0001
−1082G/A IL-10 variant
    A/A485 (42.9)219 (39.7)0.46
    A/G516 (45.6)264 (47.9)
    G/G130 (11.5)68 (12.3)
−592C/A IL-10 variant
    C/C615 (54.4)301 (54.6)0.39
    C/A449 (39.7)226 (41.0)
    A/A67 (5.9)24 (4.4)
  • Data are means ± SD or n (%), unless otherwise indicated. P values for comparisons of differences of continuous variables between two genotypes using unpaired Student’s t test. Differences in genotype frequencies were compared by χ2 test.