TABLE 3

Haplotype frequencies in type 2 diabetic patients and nondiabetic control subjects

HaplotypeNondiabetic control subjectsPatients with type 2 diabetesP*OR (95% CI)P
GCC (%)34.436.31
ACC (%)39.938.80.88 (0.72–1.06)0.16
ATA (%)25.724.90.530.91 (0.74–1.13)0.42
Haplotype frequencies in nondiabetic control subjects stratified according to BMI
HaplotypeBMI <30 kg/m2BMI >30 kg/m2P*OR (95% CI)P
GCC (%)35.233.01
ACC (%)41.138.11.00 (0.82–1.22)0.97
ATA (%)23.728.90.021.28 (1.02–1.60)0.02
Association between the number of copies of the ATA haplotypes and BMI
Number of copies of the ATA haplotypeBMI <30 kg/m2BMI >30 kg/m2P*OR (95% CI)P
0 ATA (%)57.051.01
1 ATA (%)38.541.01.13 (0.88–1.47)0.32
2 ATA (%)4.57.90.0251.96 (1.16–3.31)0.01
Association between the number of copies of the ATA haplotypes and HOMA index
Number of copies of the ATA haplotypeLower quartilesUpper quartileP*OR (95% CI)P
0 ATA (%)53.158.11
1 ATA (%)42.532.70.75 (0.54–1.04)0.08
2 ATA (%)4.49.30.0011.99 (1.12–3.53)0.01
  • *

    * P value for overall comparison by χ2 test.

  • P values and ORs (95% CI) calculated by a logistic regression analysis with adjustment for age and sex.