TABLE 5

MRI results in diabetic patients and control subjects

MRI ratingsControl subjects (n = 36)Type 1 diabetic patients (n = 37)Mean dif (95% CI)
PWML6.0 (5.0–6.0)6.0 (6.0–7.0)0.5 (−0.5 to 1.0)
DWML4.0 (2.5–6.0)3.0 (1.5–6.0)−1.0 (−3.0 to 1.5)
Cortical atrophy
    FFR (*10)0.30 ± 0.100.33 ± 0.120.01 (−0.04 to 0.06)
    SFR (*10)0.31 ± 0.080.33 ± 0.100.01 (−0.03 to 0.06)
Subcortical atrophy
    BCR0.12 ± 0.030.14 ± 0.030.01 (−0.01 to 0.02)
    BFR0.31 ± 0.050.33 ± 0.040.01 (−0.01 to 0.03)
OR (95% CI)
(Silent) infarct8%8%1.01 (0.16–6.23)
  • Data are given as unadjusted means ± SD or median (interquartile range) unless otherwise indicated. Mean dif: the adjusted between group difference (type 1 diabetic patients − control subjects) in the univariate ANOVA. Mean difference and OR were adjusted for estimated premorbid IQ and sex. FFR, frontal interhemispheric fissure ratio; SFR, Sylvian fissure ratio.