TABLE 2

Genotype frequencies of the insulin gene polymorphisms in the sample groups

MarkerGenotypeUKPDS LADA (n = 232)*W2 Repository LADA (n = 131)*Exeter YT2D LADA (n = 37)*All cases (n = 400)*Control subjects (n = 332)*
−23HphI
AA165 (0.71)81 (0.62)30 (0.81)276 (0.69)159 (0.49)
AT58 (0.25)40 (0.31)4 (0.11)102 (0.26)141 (0.43)
TT8 (0.04)10 (0.08)3 (0.08)21 (0.05)27 (0.08)
+1404Fnu4HI
CC182 (0.80)89 (0.69)30 (0.81)301 (0.76)199 (0.61)
CA42 (0.18)31 (0.24)5 (0.14)78 (0.20)105 (0.32)
AA5 (0.02)10 (0.08)2 (0.05)17 (0.04)20 (0.06)
+3580MspI
CC81 (0.35)50 (0.39)20 (0.54)151 (0.38)147 (0.45)
CT97 (0.42)60 (0.46)12 (0.32)169 (0.42)143 (0.43)
TT53 (0.23)20 (0.15)5 (0.14)78 (0.20)39 (0.12)
  • Data are n (frequency).

  • *

    * Individuals in whom genotyping was attempted.