TABLE 3

Association analysis of glucose parameters with the SNP rs2425640 and rs2425640-rs745975 haplotypes in 706 genotyped individuals from 60 Finnish FCHL families

SNP or haplotypeFrequency*AUC glucose P valueAUC insulin P valueAUC C-peptide P value
rs24256400.380.010.0080.03
rs2425640-rs745975 (H2A)0.320.010.0090.02
rs2425640-rs745975 (H2B)0.510.010.006NS
  • *

    * Allele/ haplotype frequency in all family members;

  • H2A, risk haplotype of 2-1 alleles, where 1 indicates the common allele;

  • H2B, protective haplotype of 1-1 alleles.