TABLE 2

Circulating levels of glucose, insulin, C-peptide, adipocytokines, and incretins after either an overnight fast and an OGTT, as AUC, in morbidly obese subjects before BPD and 1 week and 4 weeks after BPD

Before BPD1 week after BPD4 weeks after BPD
101010
Fasting glucose (mmol/l)7.79 ± 0.105.92 ± 0.42*4.78 ± 0.12*
Fasting insulin (pmol/l)135.72 ± 18.23107.8 ± 15.9969.04 ± 4.31
Fasting C-peptide (nmol/l)1.40 ± 0.131.05 ± 0.101.00 ± 0.08
Fasting leptin (ng/ml)51.59 ± 6.3838.56 ± 7.49*31.03 ± 3.73
Fasting adiponectin (μ g/ml)7.67 ± 0.828.49 ± 0.826.71 ± 0.36
Fasting GIP (pmol/l)13.40 ± 1.996.58 ± 1.72§5.83 ± 0.80§
Fasting GLP-1 (pmol/l)1.75 ± 0.163.42 ± 0.41§3.62 ± 0.21§
Glucose AUC (mmol/l)1,704.52 ± 91.361,146.47 ± 88.52*1,079.02 ± 47.13*
Insulin AUC (pmol/l)96,390.90 ± 12681.5153,414.30 ± 8617.14§24,776.00 ± 2249.24*
C-peptide AUC (nmol/l)589.89 ± 50.72337.77 ± 52.38289.36 ± 24.87*
GIP AUC (pmol/l)3,297.00 ± 440.601,775.70 ± 189.76§1,874.00 ± 169.60§
GLP-1 AUC (pmol/l)388.04 ± 23.40700.14 ± 84.71721.46 ± 26.70*
  • Data are means ± SE. Significant differences were observed only between pre- and postoperation groups.

  • *

    * P < 0.0001;

  • P < 0.001;

  • P < 0.05;

  • §

    § P < 0.01.