TABLE 3

Insulin mediated, whole-body glucose uptake, steady-state plasma insulin during the euglycemic-hyperinsulinemic clamp, insulin secretion at fast and after an OGTT, β-cell glucose sensitivity, β-cell sensitivity rate, and potentiation in morbidly obese subjects before and 1 and 4 weeks after BPD

Before BPD1 week after BPD4 weeks after BPD
n101010
FFM (m/kgFFM) (μm · kgFFM−1 · min−1)32.96 ± 4.3065.73 ± 3.22*64.73 ± 3.42*
Plasma insulin levels during clamp steady state (pmol/l)520.20 ± 20.16528.00 ± 24.23520.80 ± 22.85
Fasting insulin secretion (pmol/ min per m2)148.16 ± 20.0770.00.2 ± 8.1483.24 ± 8.28
Total insulin output (nmol/m2)43.76 ± 4.0725.48 ± 1.6930.50 ± 4.71
β-Cell glucose sensitivity (pmol/min per m2 per mmol/l)29.61 ± 4.2173.73 ± 4.0160.99 ± 5.44
Rate of sensitivity (nmol/m2per mmol/l)0.84 ± 0.060.44 ± 0.090.48 ± 0.09
Potentiation ratio (fold)1.29 ± 0.151.95 ± 0.211.16 ± 0.20
  • Data are means ± SE. Significant differences were observed only between pre- and postoperation groups.

  • *

    * P < 0.0001;

  • P < 0.01;

  • P < 0.05.