Case and control subjects’ tSNP analysis
SNP name | Alleles (1/2) | Allele 1 frequency in control subjects | OR (95% CI) for allele 1 | P |
---|---|---|---|---|
rs7761382 | C/T | 0.57 | 0.98 (0.89–1.08) | 0.71 |
rs6570592 | C/T | 0.46 | 1.01 (0.92–1.11) | 0.89 |
rs3818092 | G/C | 0.23 | 0.94 (0.84–1.05) | 0.25 |
rs2076683 | T/G | 0.44 | 1.04 (0.95–1.15) | 0.42 |
rs2257104 | C/A | 0.57 | 1.01 (0.92–1.11) | 0.86 |
rs2076684 | C/G | 0.09 | 0.95 (0.80–1.14) | 0.58 |
rs2064495 | T/C | 0.79 | 1.08 (0.96–1.21) | 0.20 |
Exon8-8498C>T | T/C | 0.15 | 1.06 (0.93–1.21) | 0.36 |
rs2268447 | T/C | 0.31 | 0.98 (0.89–1.08) | 0.68 |
rs2247408 | T/C | 0.31 | 0.98 (0.89–1.09) | 0.73 |
rs2328536 | T/C | 0.69 | 1.02 (0.92–1.13) | 0.68 |
rs2273323 | T/C | 0.06 | 1.02 (0.84–1.25) | 0.84 |
rs2092894 | G/A | 0.55 | 1.02 (0.93–1.12) | 0.71 |
rs6937128 | G/A | 0.25 | 0.98 (0.88–1.10) | 0.77 |
rs2064661 | C/T | 0.82 | 1.00 (0.88–1.13) | 0.99 |
The case-control study had 80% power to detect an OR >1.2–1.4. The simple allelic OR model is presented. Multiplicative, recessive, and dominant models were all tested and were also negative.