TABLE 3

State 3 and 4 respiratory activities of IMF and SS muscle mitochondria at the end of semistarvation and after 7 days of refeeding

SemistarvationIMF
SS
ControlRestrictedControlRestricted
Glutamate
    State 3750 ± 50746 ± 30341 ± 20256 ± 21*
    State 447.4 ± 2.646.0 ± 1.333.8 ± 3.226.8 ± 2.3
    RCR16.0 ± 1.116.2 ± 0.610.3 ± 0.79.6 ± 0.1
Succinate
    State 3791 ± 29757 ± 16388 ± 9338 ± 13*
    State 4181 ± 6169 ± 676.1 ± 2.177.3 ± 2.3
    RCR4.4 ± 0.14.5 ± 0.15.1 ± 0.24.4 ± 0.1*
Palmitoyl CoA
    State 3339 ± 11358 ± 22141 ± 4132 ± 7
    State 433.5 ± 0.636.6 ± 1.229.8 ± 1.425.4 ± 2.1
    RCR10.1 ± 0.39.8 ± 0.64.7 ± 0.25.3 ± 0.7
RefeedingControlRefedControlRefed
Glutamate
    State 3877 ± 19883 ± 45357 ± 21263 ± 21*
    State 449.4 ± 3.054.8 ± 1.432.5 ± 2.036.1 ± 1.4
    RCR18.1 ± 1.216.1 ± 1.411.0 ± 0.87.3 ± 0.3*
Succinate
    State 3857 ± 22982 ± 22*418 ± 16406 ± 25
    State 4177 ± 7188 ± 286.8 ± 3.482.7 ± 4.4
    RCR4.8 ± 0.25.2 ± 0.14.8 ± 0.14.9 ± 0.2
Palmitoyl CoA
    State 3359 ± 25380 ± 21154 ± 5125 ± 6*
    State 439.2 ± 1.842.3 ± 3.026.5 ± 0.928.6 ± 3.2
    RCR9.1 ± 0.39.0 ± 0.65.8 ± 0.44.6 ± 0.2
  • Data are means ± SE of six different experiments and are expressed as ng atoms oxygen · min−1 · mg−1 protein. RCR, respiratory control ratio.

  • *

    * P < 0.05 compared with controls.