Insulin secretion
| n | Pulse mass (pmol/pulse) | Pulse amplitude (pmol/min) | Pulse interval (min) | Total secretion (pmol · kg−1 · min−1) | Insulin clearance (l/min) | |
|---|---|---|---|---|---|---|
| Basal | ||||||
| Sham surgery | 7 | 129 ± 25 | 83 ± 15 | 5.3 ± 0.5 | 2.4 ± 0.4 | 0.7 ± 0.1 |
| Partial pancreatectomy | 7 | 51 ± 14* | 35 ± 9† | 4.5 ± 0.4 | 1.2 ± 0.3† | 0.4 ± 0.1† |
| Meal | ||||||
| Sham surgery | 7 | 424 ± 97 | 310 ± 76 | 5.3 ± 0.3 | 8.6 ± 1.7 | 0.9 ± 0.2 |
| Partial pancreatectomy | 7 | 359 ± 99 | 258 ± 76 | 5.3 ± 0.5 | 6.2 ± 1.4 | 0.4 ± 0.1† |
| Hyperglycemic clamp | ||||||
| Sham surgery | 7 | 596 ± 184 | 453 ± 142 | 4.9 ± 0.4 | 10.5 ± 2.5 | 0.8 ± 0.1 |
| Partial pancreatectomy | 6 | 123 ± 51† | 102 ± 40† | 5.0 ± 1.2 | 3.1 ± 0.9† | 0.6 ± 0.2 |
Data are means ± SE.
* P < 0.01,
† P < 0.05 for partial pancreatectomy vs. sham surgery.