TABLE 1

Recognition of hIns B5–14 and A2–10 by islet-infiltrating T-cells from NOD.β2mnull.HHD mice

MouseSpot-forming cells*
MouseSpot-forming cells*
Ins1 B5–14Ins2/hIns B5–14Ins1/2 A2–10hIns A2–10
182212170
25281226196
3125673282105
47924519204
5632525287
63020
718320
816814
92161
103158
111706
  • *

    * Islet-infiltrating T-cells were cultured individually from nondiabetic female NOD.β2mnull.HHD mice, and their reactivity to the indicated peptides was measured by IFN-γ ELISPOT. Numbers of spot-forming cells per 2 × 104 cells are indicated.