TABLE 2

Characteristics of clusters identified by SPM at statistical threshold of P < 0.001

Cluster sizeT (peak value in cluster)P (corrected cluster level)xyz
Increased uptake (across both groups)
    Left ventral striatum74916.658.3e-7−2227
    Right ventral striatum6869.892.1e-618123
    Occipital cortex2,0088.941.5e-136−8117
Decreased uptake (across both groups)
    White matter20,57017.750202813
    Left inferior frontal gyrus3139.450.0013−55251
    Right inferior frontal gyrus3568.460.000575917−1
    Right anterior white matter*84517.751.0e-14202813
    Right periventricular white matter*2,64616.30024−3138
    Brainstem*2,42716.2704−7−16
    Left periventricular white matter*4,86414.750−16−3529
    Left inferior frontal gyrus*1199.450.00041−55251
Greater increase in aware than in unaware subjects
    Occipital cortex3656.600.0004−2−933
    Left amygdala3056.65NS−301−15
    Occipital cortex1,8516.606.5e-5−2−933
    Left ventral striatum1965.54NS−2407
    Left cerebellum1915.24NS−46−46−21
    Medial cerebellum/brainstem2,8615.246.8e-76−42−18
Greater decrease in aware than in unaware subjects
    Brodmann areas 10, 11, and 47 (right)1,0715.480.00413632−13
    Brodmann areas 10, 45, and 46 (right)4144.37NS513017
    Brodmann areas 8 and 9 (right)2144.22NS242341
  • Clusters of voxels reaching significance, P < 0.001 (uncorrected) and minimum cluster size of 100 voxels (unless otherwise stated). T is peak t statistic within cluster; P is corrected for the cluster (not the voxel). Coordinates of the peak voxel are given in Talairach space.

  • * Threshold of P < 0.0001, cluster size >100;

  • P < 0.01, cluster size >100. NS, not significant.