TABLE 1

Vildagliptin-regulated hepatic gene expression

WTDIRKO
Mvk+
Acadm+
Acsl1+
Mvd+
Fdft1++
Cpt1+
Acaa1+
Crat
Acads
Hadha
Apo-4
Apo-C
Apo-m
Lipg
Acab
Fads1
Fads 2
Scd1
Lss
Dhcr7
Sqle
  • +, Significant effect of vildagliptin on levels of mRNA transcripts; −, lack of effect of vildagliptin. Abbreviation of mRNA transcripts are as per gene nomenclature for murine genes.