TABLE 2

SNPs most significantly associated with type 2 diabetes

dbSNP rsChr.Position*Gene*Allele 1/2Control frequency (a2)Case frequency (a2)POR
rs19324651104418527C/G0.8810.9585.61 × 10−63.102
rs104977232192817829TMEFF2A/G0.1950.0958.45 × 10−60.431
rs14980244125912629SPRY1/ANKRD50C/T0.8440.7351.68 × 10−50.513
rs61366512019144096SLC24A3A/G0.8340.7251.81 × 10−50.525
rs75770578313535ICA1/NXPH1A/G0.4980.632.79 × 10−51.713
rs8618442220330773SDF2L1G/T0.0860.1723.21 × 10−52.214
rs105184424125951873ANKRD50A/C0.8610.7613.22 × 10−50.516
rs104922021266628005DYRK2/IFNGC/T0.110.2033.48 × 10−52.054
rs115900610100396273HPSE2C/T0.2660.394.01 × 10−51.765
rs105123329104554018OR13D1C/T0.7890.6784.60 × 10−50.564
rs15365581097222258SORBS1G/T0.2610.1554.77 × 10−50.519
rs1941011185649096EPB41L3A/T0.6750.5514.96 × 10−50.590
rs4586852130099382GRIK1A/G0.1050.1946.54 × 10−52.048
rs28316052128467064A/G0.9450.8746.82 × 10−50.405
  • *

    * Affymetrix NetAffx annotation;

  • allele 2 vs. 1. Chr., chomosome.