TABLE 3

SNPs associated with type 2 diabetes in Mexican Americans (P < 0.001) with replication in at least one other 100K GWAS

dbSNP rsChr.Position*Gene*Allele 1/2Mexican Americans (P value)Mexican Americans (OR)Amish (P value)Amish (OR)Pima Indians (CC P)§Pima Indians (CC OR)§Pima Indian sibs (P)Pima Indian sibs (OR)FHS GEE (P)FHS FBAT (P)#FHS HRR**
rs979752115495715UBQLNL/OR52H1C/T0.000120.5620.0300.7640.0400.6580.709
rs71647731558855240RORAC/T0.000161.6390.0211.300
rs981864928293495LINGO2G/T0.000242.1380.0201.035
rs10498761645850484A/C0.000361.6750.0411.290
rs15176452223998255C/G0.000720.4750.0050.766
rs3775745471293834CSN3A/C0.000780.6360.0020.698
rs18337145148035093HTR4/ADRB2C/T0.000780.6430.0260.713
rs27730801175428407RALGPS2A/G0.000800.6280.0330.793
rs15099571064280724EGR2A/G0.000840.6520.0320.721
rs39228121175391590RALGPS2/ANGPTL1A/G0.000881.5230.0281.311
rs10516322418099836LCORL/NCAPGC/G0.000890.6560.0500.806
rs69293706145395271UTRNC/T0.000951.5330.0333.988
  • *

    * Affymetrix NetAffx annotation;

  • allele 2 vs. 1;

  • genotype 22 vs. 12;

  • §

    § case-control tests, allele 2 vs. 1;

  • within-family tests, allele 2 vs. 1;

  • generalized estimating equations (GEEs), allele 2 vs. 1;

  • #

    # family-based association test (FBAT), allele 2 vs. 1;

  • **

    ** hazard rate ratio (HRR), allele 2 vs. 1. Chr., chromosome.