SNPs associated with type 2 diabetes in Mexican Americans (P < 0.001) with replication in at least one other 100K GWAS
| dbSNP rs | Chr. | Position* | Gene* | Allele 1/2 | Mexican Americans (P value)† | Mexican Americans (OR)† | Amish (P value)‡ | Amish (OR)‡ | Pima Indians (CC P)§ | Pima Indians (CC OR)§ | Pima Indian sibs (P)‖ | Pima Indian sibs (OR)‖ | FHS GEE (P)¶ | FHS FBAT (P)# | FHS HRR** |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| rs979752 | 11 | 5495715 | UBQLNL/OR52H1 | C/T | 0.00012 | 0.562 | 0.030 | 0.764 | 0.040 | 0.658 | 0.709 | ||||
| rs7164773 | 15 | 58855240 | RORA | C/T | 0.00016 | 1.639 | 0.021 | 1.300 | |||||||
| rs981864 | 9 | 28293495 | LINGO2 | G/T | 0.00024 | 2.138 | 0.020 | 1.035 | |||||||
| rs10498761 | 6 | 45850484 | A/C | 0.00036 | 1.675 | 0.041 | 1.290 | ||||||||
| rs1517645 | 2 | 223998255 | C/G | 0.00072 | 0.475 | 0.005 | 0.766 | ||||||||
| rs3775745 | 4 | 71293834 | CSN3 | A/C | 0.00078 | 0.636 | 0.002 | 0.698 | |||||||
| rs1833714 | 5 | 148035093 | HTR4/ADRB2 | C/T | 0.00078 | 0.643 | 0.026 | 0.713 | |||||||
| rs2773080 | 1 | 175428407 | RALGPS2 | A/G | 0.00080 | 0.628 | 0.033 | 0.793 | |||||||
| rs1509957 | 10 | 64280724 | EGR2 | A/G | 0.00084 | 0.652 | 0.032 | 0.721 | |||||||
| rs3922812 | 1 | 175391590 | RALGPS2/ANGPTL1 | A/G | 0.00088 | 1.523 | 0.028 | 1.311 | |||||||
| rs10516322 | 4 | 18099836 | LCORL/NCAPG | C/G | 0.00089 | 0.656 | 0.050 | 0.806 | |||||||
| rs6929370 | 6 | 145395271 | UTRN | C/T | 0.00095 | 1.533 | 0.033 | 3.988 |
* Affymetrix NetAffx annotation;
† allele 2 vs. 1;
‡ genotype 22 vs. 12;
§ case-control tests, allele 2 vs. 1;
‖ within-family tests, allele 2 vs. 1;
¶ generalized estimating equations (GEEs), allele 2 vs. 1;
# family-based association test (FBAT), allele 2 vs. 1;
** hazard rate ratio (HRR), allele 2 vs. 1. Chr., chromosome.