TABLE 5

SNPs associated with type 2 diabetes in Mexican Americans (P < 0.01) with replication in more than one other GWAS

dbSNP rsChr.Position*Gene*Allele (1/2)Mexican American (P)Mexican American (OR)Amish (P)Amish (OR)Pima Indian case-control (P)§Pima Indian case-control (OR)§Pima Indian sibs (P)Pima Indian sibs (OR)FHS GEE (P)FHS FBAT (P)#FHS HRR**DGI (rs)DGI (P)DGI (OR)
rs979752115495715UBQLNL/OR52H1C/T0.000120.5620.0300.7640.0400.6580.709
rs27730801175428407RALGPS2A/G0.000800.6280.0330.793
rs15099571064280724EGR2A/G0.000840.6520.0320.721642807240.008200.831
rs39228121175391590RALGPS2/ANGPTL1A/G0.000881.5230.0281.311
rs21916789119433899DBC1A/G0.003160.6780.0350.5430.0090.797
rs207717311117997801PHLDB1A/G0.005030.7030.0300.7960.0350.651
rs3602482126731609GYPCC/G0.006020.6760.0140.618rs3602560.0170.881
rs10504319862089326MGC34646/CHD7C/T0.006560.5710.0100.5490.0430.726rs15099570.0080.831
rs10500641115426152C/T0.006561.522rs13916190.014890.746
rs18453861829572254C/G0.009011.3980.0451.487rs72373790.0051.203
  • *

    * Affymetrix NetAffx annotation;

  • allele 2 vs. 1;

  • genotype 22 vs. 12;

  • §

    § case-control tests, allele 2 vs. 1;

  • within-family tests, allele 2 vs. 1;

  • generalized estimating equations (GEEs), allele 2 vs. 1;

  • #

    # family-based association test (FBAT), allele 2 vs. 1;

  • **

    ** hazard rate ratio (HRR), allele 2 vs. 1. Chr., chromosome.