TABLE 2

Systemic insulin measures

Week of HF dietITT ΔAUCSerum insulin (ng/ml)
1 week baseline0.24 ± 0.08*
41,197.5 ± 583.3*0.32 ± 0.09*
83,992.8 ± 486.9†1.51 ± 0.19†
126,998.4 ± 900.6†‡1.30 ± 0.0.39†
167,728.8 ± 663.9‡1.12 ± 0.23†‡
204,628.7 ± 1143.0†1.38 ± 0.18†
  • Data are means ± SE. Differences in ITT glucose AUC (ΔAUC) between HF-fed and LF-fed mice (n = 5–9) and fasted serum insulin in HF-fed mice (n = 4) during the DIO time course (see research design and methods). Means identified by the same symbol are not significantly different (P < 0.05) by Tukey’s procedure.