TABLE 1

Description of sample characteristics for type 2 diabetes GWAS in the Amish

CharacteristicsType 2 diabetic case and NGT control subject dataset
Type 2 diabetic case subjectsNGT control subjects
n124295
Male subjects (%)3352
Age (years)51.3 ± 10.564.4 ± 12.9
BMI (kg/m2)29.3 ± 5.827.4 ± 4.7
CharacteristicsOGTT-derived quantitative trait dataset
AllMenWomen
n427200227
Age (years)51.9 ± 11.952.2 ± 11.951.7 ± 11.9
BMI (kg/m2)27.7 ± 5.026.4 ± 4.028.9 ± 5.5
Fasting glucose (mmol/l)5.09 ± 0.455.12 ± 0.475.07 ± 0.43
GAUC (mmol · l−1 · h−1)379.2 ± 68.0362.6 ± 65.3393.9 ± 67.1
IAUC (mU· l−1 · h−1)137.9 ± 88.9108.5 ± 60.6164.5 ± 101.3
HOMA-IR (mU per mmol/l2)2.6 ± 1.72.6 ± 2.22.6 ± 1.1
ISI (units/g)0.9 ± 1.50.85 ± 1.90.93 ± 1.0
  • Data are means ± SD. All were nondiabetic subjects.