TABLE 2

Log(IL-6) by IL6R genotypes in healthy control and diabetes case subjects

	Healthy women					P*	FDR	Diabetic women				P*	FDR
		11	12	22		P*	FDR		11	12	22	P*	FDR
SNP1	246	317	114			223	299	99
	0.66 ± 0.04	0.61 ± 0.04	0.68 ± 0.06	0.51	0.60	0.85 ± 0.04	0.92 ± 0.04	0.86 ± 0.07	0.34	0.45
SNP2	409	243	37			394	208	25
	0.64 ± 0.03	0.62 ± 0.04	0.76 ± 0.11	0.94	0.94	0.92 ± 0.03	0.85 ± 0.05	0.99 ± 0.14	0.29	0.41
SNP3	222	357	112			215	303	110
	0.61 ± 0.05	0.66 ± 0.04	0.68 ± 0.07	0.38	0.47	0.88 ± 0.04	0.91 ± 0.04	0.87 ± 0.06	0.62	0.69
SNP4	238	341	107			235	309	87
	0.54 ± 0.04	0.67 ± 0.04	0.76 ± 0.07	0.005	0.02	0.81 ± 0.04	0.90 ± 0.04	1.10 ± 0.07	0.018	0.05
SNP5	215	345	114			176	325	119
	0.72 ± 0.05	0.63 ± 0.04	0.50 ± 0.06	0.039	0.07	0.99 ± 0.05	0.90 ± 0.04	0.77 ± 0.06	0.035	0.07
SNP6	225	355	105			225	312	96
	0.51 ± 0.05	0.68 ± 0.04	0.75 ± 0.07	0.0008	0.008	0.80 ± 0.04	0.91 ± 0.04	1.08 ± 0.07	0.01	0.03
SNP7	239	347	105			227	308	88
	0.51 ± 0.04	0.69 ± 0.04	0.76 ± 0.07	0.0005	0.008	0.79 ± 0.04	0.91 ± 0.04	1.11 ± 0.07	0.004	0.02
SNP8	476	197	17			448	171	12
	0.65 ± 0.03	0.64 ± 0.05	0.45 ± 0.17	0.66	0.69	0.92 ± 0.03	0.80 ± 0.05	1.19 ± 0.18	0.12	0.20
SNP9	405	253	27			362	237	32
	0.69 ± 0.03	0.57 ± 0.04	0.53 ± 0.13	0.02	0.05	0.96 ± 0.03	0.82 ± 0.04	0.74 ± 0.11	0.008	0.03
SNP10	462	218	17			412	198	19
	0.68 ± 0.03	0.55 ± 0.05	0.64 ± 0.17	0.026	0.06	0.92 ± 0.03	0.86 ± 0.05	0.65 ± 0.15	0.23	0.35

Data are n or means±SE. For each polymorphism, 11 represents the major allele homozygotes, 12 represents the heterozygotes, and 22 represents the minor allele homozygotes; missing genotyping is not included.
*
* Comparisons between carriers and noncarriers; adjusted for age, BMI, alcohol consumption, smoking, physical activity, family history of diabetes, and menopausal status.