TABLE 2

Log(IL-6) by IL6R genotypes in healthy control and diabetes case subjects

Healthy women
P*FDRDiabetic women
P*FDR
111222111222
SNP124631711422329999
0.66 ± 0.040.61 ± 0.040.68 ± 0.060.510.600.85 ± 0.040.92 ± 0.040.86 ± 0.070.340.45
SNP24092433739420825
0.64 ± 0.030.62 ± 0.040.76 ± 0.110.940.940.92 ± 0.030.85 ± 0.050.99 ± 0.140.290.41
SNP3222357112215303110
0.61 ± 0.050.66 ± 0.040.68 ± 0.070.380.470.88 ± 0.040.91 ± 0.040.87 ± 0.060.620.69
SNP423834110723530987
0.54 ± 0.040.67 ± 0.040.76 ± 0.070.0050.020.81 ± 0.040.90 ± 0.041.10 ± 0.070.0180.05
SNP5215345114176325119
0.72 ± 0.050.63 ± 0.040.50 ± 0.060.0390.070.99 ± 0.050.90 ± 0.040.77 ± 0.060.0350.07
SNP622535510522531296
0.51 ± 0.050.68 ± 0.040.75 ± 0.070.00080.0080.80 ± 0.040.91 ± 0.041.08 ± 0.070.010.03
SNP723934710522730888
0.51 ± 0.040.69 ± 0.040.76 ± 0.070.00050.0080.79 ± 0.040.91 ± 0.041.11 ± 0.070.0040.02
SNP84761971744817112
0.65 ± 0.030.64 ± 0.050.45 ± 0.170.660.690.92 ± 0.030.80 ± 0.051.19 ± 0.180.120.20
SNP94052532736223732
0.69 ± 0.030.57 ± 0.040.53 ± 0.130.020.050.96 ± 0.030.82 ± 0.040.74 ± 0.110.0080.03
SNP104622181741219819
0.68 ± 0.030.55 ± 0.050.64 ± 0.170.0260.060.92 ± 0.030.86 ± 0.050.65 ± 0.150.230.35
  • Data are n or means±SE. For each polymorphism, 11 represents the major allele homozygotes, 12 represents the heterozygotes, and 22 represents the minor allele homozygotes; missing genotyping is not included.

  • *

    * Comparisons between carriers and noncarriers; adjusted for age, BMI, alcohol consumption, smoking, physical activity, family history of diabetes, and menopausal status.