Comparisons of allele frequencies in the Norwegian sample of 1,644 type 2 diabetic and 1,879 control subjects
Marker | Position (bp)† | Minor/major allele | Minor allele frequency | Allelic OR* | ||||
---|---|---|---|---|---|---|---|---|
Case subjects | Control subjects | OR (95% CI) | P | |||||
rs1884613 | −3925 | G/C | 0.198 | 0.181 | 1.17 (1.03–1.35) | 0.02 | ||
rs2144908 | 1377 | A/G | 0.197 | 0.178 | 1.21 (1.05–1.38) | 0.007 | ||
rs6103716 | 15290 | C/A | 0.339 | 0.338 | 1.03 (0.92–1.16) | 0.57 | ||
rs6065725 | 20675 | A/G | 0.314 | 0.316 | 0.99 (0.88–1.11) | 0.89 | ||
rs6017335 | 26485 | A/G | 0.486 | 0.467 | 1.06 (0.96–1.18) | 0.26 | ||
rs6031580 | 30941 | A/G | 0.272 | 0.280 | 0.96 (0.85–1.08) | 0.46 | ||
rs4812831 | 33920 | A/G | 0.113 | 0.097 | 1.21 (1.02–1.44) | 0.03 | ||
rs3092370 | 35763 | A/G | 0.469 | 0.482 | 0.93 (0.83–1.03) | 0.16 | ||
rs717248 | 41265 | G/A | 0.030 | 0.032 | 0.96 (0.70–1.32) | 0.81 | ||
rs717247 | 41444 | G/A | 0.301 | 0.313 | 0.93 (0.83–1.05) | 0.24 | ||
rs1028583 | 66421 | T/G | 0.354 | 0.358 | 0.98 (0.88–1.10) | 0.76 | ||
rs3818247 | 73140 | T/G | 0.330 | 0.347 | 0.92 (0.82–1.03) | 0.15 |
* Calculations based on logistic regression with age, BMI, and sex as cofactors.
† Position relative to start of the HNF4A P2 promotor (according to Goldenpath: hg17; dbSP: build 123).