TABLE 2

Body composition (%) at end point in candy-fed obese (DIO) and lean control rats (Chow) and in candy-fed obese liraglutide-, vildagliptin-, or chow-only–treated rats (DIO-Chow)

ChowLiraglutideVildagliptinDIODIO-Chow
Whole-body lean mass83.3 ± 1.2*80.2 ± 1.672.9 ± 3.270.9 ± 1.6§84.7 ± 1.7
Whole-body fat mass11.3 ± 1.1*15.5 ± 1.722.5 ± 2.924.6 ± 1.79.2 ± 1.4
Whole-body bone mineral content3.3 ± 0.13.6 ± 0.13.3 ± 0.13.5 ± 0.13.3 ± 0.1
  • Data are means ± SE, analyzed by ANOVA and Bonferroni multiple comparison subtest.

  • *

    * P < 0.001 vs. DIO control;

  • P < 0.05 vs. vildaglitptin;

  • P < 0.001 vs. Chow;

  • §

    § P < 0.001 vs. liraglutide;

  • P < 0.01 vs. liraglutide.