TABLE 1

Cell death during hypoxic and normoxic conditions according to islet size

Culture condition
Cell death (hematoxylin and eosin)
Islet size
<50 μm50–100 μm>100 μm
24 h normoxia3.2 ± 0.6%5.8 ± 0.8%8.8 ± 1.8%
    n*615820
24 h hypoxia9.7 ± 1.4%12.4 ± 1.2%17.5 ± 3.0%
    n54488
48 h normoxia5.0 ± 1.1%6.8 ± 0.7%6.6 ± 1.3%
    n406716
48 h hypoxia7.7 ± 1.7%10.9 ± 1.3%23.5 ± 11.3%
    n44403
  • Data are means ± SE.

  • *

    * n = number of islets analyzed.