TABLE 3

Genotype frequencies of TNFAIP3 tag SNPs in the Boston population according to CAD status

CADCAD+P value*OR (95% CI)*
n240239
rs583522
    A/A0.5540.4351.0
    A/G0.3670.5021.7 (1.1–2.5)
    G/G0.0790.0630.0421.1 (0.5–2.3)
rs5029930
    A/A0.8500.7531.0
    A/C + CC0.1500.2470.0012.3 (1.4–3.8)
rs5029933
    A/A0.9000.8581.0
    A/G + G/G0.1000.1420.071.8 (0.9–3.2)
rs610604
    A/A0.5250.3681.0
    A/C0.3920.5111.9 (1.3–2.9)
    C/C0.0830.1210.0032.3 (1.1–4.5)
rs636617
    C/C0.6580.7071.0
    C/T0.3170.2760.7 (0.5–1.1)
    T/T0.0250.0170.340.7 (0.2–3.0)
  • * Adjusted for age, sex, BMI, smoking status, hypertension status, and A1C.

  • Minor allele homozygotes had expected counts <5.

  • P = 0.0008 for C/C + A/C vs. A/A.