TABLE 4

Fatty acid composition of cardiac lipids

Fatty acidComposition
Heart mitochondria
Heart phospholipids
Nonphosphorous lipids
ControlAMPKα2−/−ControlAMPKα2−/−ControlAMPKα2−/−
16:013.4 ± 0.614.6 ± 0.714.2 ± 0.916.4 ± 0.519.8 ± 0.518.1 ± 0.4
16:1ω91.1 ± 0.21.0 ± 0.30.3 ± 0.10.35 ± 0.036.2 ± 0.74.5 ± 0.3
18:018 ± 117 ± 121 ± 121 ± 18.9 ± 0.39 ± 1
18:1ω96.7 ± 0.37.0 ± 0.26.3 ± 0.36.3 ± 0.319.0 ± 0.422.0 ± 0.4*
18:1ω72.51 ± 0.032.7 ± 0.12.26 ± 0.042.5 ± 0.11.4 ± 0.11.5 ± 0.3
18:2ω6 LA19.2 ± 0.616.8 ± 0.4*18.0 ± 0.216.3 ± 0.5*20.1 ± 1.524.3 ± 0.3*
20:4ω64.5 ± 0.24.3 ± 0.25.2 ± 0.24.9 ± 0.33.0 ± 0.12.6 ± 0.4
22:5ω31.02 ± 0.031.2 ± 0.11.1 ± 0.14.1 ± 3.11.5 ± 0.11.5 ± 0.4
22:6ω330 ± 231 ± 228 ± 224 ± 15.1 ± 0.45.4 ± 0.6
SFA32 ± 133 ± 136 ± 234 ± 536 ± 139 ± 5
MUFA12 ± 111 ± 19.7 ± 0.39 ± 131 ± 136 ± 6
PUFAω625.1 ± 0.522.5 ± 0.6*25.2 ± 0.420 ± 325 ± 133 ± 5
PUFAω331 ± 233 ± 229 ± 224 ± 48.1 ± 0.39 ± 1
  • Data are means±SE (%). LA, linoleic acid; MUFA, monounsaturated fatty acid; PUFA, polyunsaturated fatty acid; SFA, saturated fatty acid. Three control and three AMPKα2−/− mice were used.

  • *

    * P < 0.05.