TABLE 3

Effect of acipimox and insulin on glucose metabolism

Endogenous glucose productionGlucose disposalGlucose oxidationNonoxidative glucose metabolismFat oxidation
Pre-acipimox
    Basal1.94 ± 0.091.33 ± 0.080.59 ± 0.100.77 ± 0.07
    Insulin0.1 ± 0.075.28 ± 0.462.90 ± 0.182.51 ± 0.350.18 ± 0.05
Post-acipimox
    Basal1.97 ± 0.101.52 ± 0.09§0.46 ± 0.090.66 ± 0.04§
    Insulin0.01 ± 0.01§6.31 ± 0.552.87 ± 0.223.12 ± 0.430.18 ± 0.04
  • Data are means ± SE.

  • P < 0.01 vs. basal,

  • P < 0.05 vs. pre-acipimox,

  • §

    § P < 0.01 vs. pre-acipimox.